10-Hydroxycamptothecine

 Name: 10-Hydroxycamptothecine
Origin: Bark
Spec: ≥98.0%
Appearance: Light-yellow powder
CAS NO.: 19685-09-7
MW: 364.35
MF: C20H16N2O5
Formula:             

Effect:
10-hydroxycamptothecin is the derivative of camptothecine that is a micro-alkaloid from camptotheca Acuminate. is a kind of pharmaceutical intermediate, an alkaloid originally isolated from the Camptotheca acuminata, exerted inhibitory effects on DNA topoisomerase (Topo )[1]and has anticancer activity in vitro and in vivo. It can also induce differentiation of leukemia MELC[2]and HL-60[3]cells. The purpose of this study is to investigate the proliferation-inhibiting and differentiation-inducing actions of HCPT on human hepatoma Hep G2 cells.

Package: 1KG/bag  5KG/durm