+86-29-65656900 (24 hours)

Active Ingredients

 

Hirudin

Name: Hirudin
Origin: Hirudin extract from leech
Spec: ≥98%
Appearance: white powder
CAS NO.: 113274-56-9
MW: 1468.53
MF: C66H93N13O25

Effect:
A,Hirudin is a naturally occurring peptide in the salivary glands of medicinal leeches (Hirudo medicinalis) that has a blood anticoagulant property. This is fundamental for the leeches’ alimentary habit of hematophagy, since it keeps the blood flowing after the initial phlebotomy performed by the worm on the host’s skin
B,Thrombin is produced from prothrombin, by the action of an enzyme, prothrombinase, in the final states of coagulation. Fibrin is then cross linked by factor XIII to form a blood clot. The principal inhibitor of thrombin in normal blood circulation is antithrombin III.

C,Similar to antithrombin III, the anticoagulatant activity of hirudin is based on its ability to inhibit the pro-coagulant activity of thrombin.Hirudin is the most potent natural inhibitor of thrombin. Unlike antithrombin III hirudin binds to and inhibits only the activity of thrombin forms with a specific activity against fibrinogen.
D,Therefore, hirudin prevents or dissolves the formation of clots and thrombi (i.e. it has a thrombolytic activity), and has therapeutic value in blood coagulation disorders, in the treatment of skin hematomas and of superficial varicose veins, either as an injectable or a topical application cream. In some aspects, hirudin has advantages over more commonly used anticoagulants and thrombolytics, such as heparin, as it does not interfere with the biological activity of other serum proteins and can also act on complexed thrombin.

Package: 1KG/bag 25KG/durm

Share to:
Clicks:  Update time:2013-03-15
Previous:Salicin
Next:Usinic acid

Contact us

Name:Xi’an Herbking Biotechnology Co., Ltd
Add:No.8 Keji 5Rd, Gaoxin District Xi’an 710075 China
Tel:+86-29-65656900 81885682
Fax:+86-29-8188 5682
E-mail:sales@herbking.com.cn

Concern us

Share to:
1688
Copyright © 2017-2018 All Rights Reserved Copyright:Xi’an Herbking Biotechnology Co., Ltd 陕ICP备15007638号 Technical Support:DuZhuo

免责声明:本网站部分图片和文字来源于网络,版权归原作者或者原公司所有,如果您觉得侵犯了您的权利,请告知我们立即删除,谢谢!